| Khoom npe | Polyquaternium-1 |
| Synonym | Polidronium Chloride, PQ-1, Polyquad, Onamer M |
| CAS Nr. | 75345‑27‑6 |
| Qhov tshwm sim | Tawm-dawb mus rau amber / lub teeb-xim av khoom, hygroscopic heev |
| Molecular Formula | C₇H₈N₄O₂ |
| Molecular Luj | 180.16 g / mol |
| Purity | Ntau dua lossis sib npaug li 98% HPLC |
| Pob | Txias-pack / ice-pack tsheb thauj mus los, yuav tsum muaj teeb pom kev zoo |
| Cia | Muab kaw, txias thiab qhuav qhov chaw, -20℃pom zoo rau kev khaws cia ntev |
| Txee-Lub neej | 24 Lub Hlis |
Khoom Description
Polyquaternium-1 yog dab tsi?
Polyquaternium-1, tseem hu ua PQ-1 lossis Polidronium Chloride (CAS:75345-27-6), yog cationic polymeric quaternary ammonium compound. Nws zoo nkaus li amber-xim av heev hygroscopic khoom khoom. Raws li antimicrobial polymeric preservative, nws cuam tshuam nrog microbial cell membranes ntawm polycationic zog. Nws yog dav siv rau ophthalmic formulation R&D, contact-lens care solution research and cosmetic preservative screening. Rau kev tshawb fawb siv nkaus xwb. Tsis yog rau kev thov ncaj qha rau tib neeg yam tsis muaj kev tswj xyuas tiav.
Hauv qab no yog lwm yam polyquaternium cationic polymer analogs dua li Polyquaternium-1. Lawv yog dav siv nyob rau hauv ophthalmic preservative kev tshawb fawb, cosmetic conditioning, film-forming thiab anti-static formulation txoj kev loj hlob. COA, SDS thiab bulk-supply service muaj rau cov khoom no.
| Khoom npe | CAS Nr | Cov yam ntxwv tseem ceeb & Lub ntsiab R & D Daim Ntawv Thov |
| Polyquaternium-1 (PQ-1, Polidronium Chloride) | 75345‑27‑6 | Cationic polymeric preservative; ophthalmic & contact-lens solution formulation research, low-cell-toxicity antimicrobial screeningPMC |
| Polyquaternium-7 | 26062‑79‑3 | DADMAC-acrylamide copolymer; Kev kho plaub hau, tshuaj tiv thaiv zoo li qub, tshuaj zawv plaub hau & tshuaj ntxuav lub cev R & D |
| Polyquaternium-10 | 68610‑92‑4 | Cation-modified hydroxyethyl cellulose; cov plaub hau txias, zaj duab xis-forming tus neeg saib xyuas rau pob tshab cov tshuaj pleev ib ce |
| Polyquaternium-11 | 53633‑54‑8 | VP-DMAEMA copolymer; styling zaj duab xis-yav dhau los, anti-static rau cov plaub hau-tu & styling-prototyping |
| Polyquaternium-22 | 53694‑17‑0 | DADMAC-acrylic acid amphoteric polymer; wide-pH-range conditioner rau cov plaub hau-dye & relaxer formula tshawb fawb |
| Polyquaternium-16 | 95144‑24‑4 | Vinylpyrrolidone-vinylimidazole quaternary copolymer; plaub hau kho, antistatic rau tshuaj pleev ib ce R & D |
| Polyquaternium-37 | 26161‑33‑1 | Cross-linked cationic acrylic polymer; thickener & conditioning agent rau kev tu tawv nqaij & plaub hau kev tu tshuab |
Kev siv ntawm Polyquaternium-1
1.Ophthalmic Formulation R&D Preservative kev tshuaj ntsuam xyuas rau kev sib cuag-lens multipurpose tov prototypes, kev tshawb fawb tsim kua muag tsim, kev tsim kho qhov muag ntau qhov muag; Kev soj ntsuam raws li lwm txoj hauv kev rau benzalkonium chloride (BAK) rau txo qhov muag pom kev ua xua.
2.In-vitro Antimicrobial & Biocide Research Laboratory kuaj rau bacteriostatic / fungicidal kev ua tau zoo, kev soj ntsuam cytotoxicity tawm tsam pob txha epithelial cells, preservative-effectiveness method validation for pharmaceutical excipient projects.
3.Pharmaceutical Excipient Compatibility Study Compatibility kuaj nrog buffers, surfactants thiab lwm yam ophthalmic excipients; Kev ntsuas kev ruaj ntseg ntawm ntau cov khoom siv aqueous ophthalmic.
4.Cosmetic Preservative Screening R&D kev tshuaj ntsuam xyuas rau cov qauv tshuaj pleev ib ce qis qis; txwv kev siv tshuaj pleev ib ce tiag tiag hauv ntiaj teb, feem ntau yog tsom rau kev soj ntsuam ophthalmic-uas nyob ib sab cosmetic-raw-material.
Cov txiaj ntsig ntawm Polyquaternium-1
1.Enables low-irritation preservative-system prototyping Muab ib tug siv tau polymeric lwm txoj rau BAK; pab cov kws tsim qauv tsim cov tshuaj ntau yam ophthalmic prototypes nrog txo qis hauv vitro cytotoxic txaus ntshai rau kev tshuaj ntsuam ocular-cell-based.
2.Stable antimicrobial kev ua tau zoo nyob rau hauv ophthalmic pH qhov rais Retains preservative kev ua tau zoo thoob plaws formulation pH, txo ntxiv kev hloov ua hauj lwm rau aqueous ophthalmic systems.
3. Kev sib raug zoo nrog cov khoom siv hluav taws xob ophthalmic zoo sib xws nrog cov buffers thiab cov tshuaj solubilizers, txiav cov khoom ua haujlwm rau kev sib raug zoo-validation thwmsim.
4. Cov cuab yeej muaj txiaj ntsig zoo rau kev siv tshuaj tiv thaiv kab mob R&D Cov khoom pov thawj me me ntawm cov khoom siv lo ntsiab muag, txhawb kev txhim kho ntau lub hom phiaj lens-care formula prototypes.
5.Cov khoom zoo sib xws txo qis R & D tsis paub meej Tsawg-tsis muaj paug, cov khoom siv raw khoom zoo txo qis kev sib tw ua haujlwm sib txawv, ua kom koj cov txheej txheem iteration.
6.Broad reference bases for preservative-comparison studies Well-documented reference compound, yooj yim rau sab-los-sab benchmarking tiv thaiv lwm yam quaternary-type preservatives nyob rau hauv koj lub lab tej yaam num.
Polyquaternium-1 vs Traditional Preservatives (BAK) Sib piv
Hauv ophthalmic thiab multi-dose aqueous formulation kev tshawb fawb, Benzalkonium Chloride (BAK) tau ntev ua lub ntsiab tseem ceeb preservative benchmark. Polyquaternium-1 (PQ-1) tau kawm dav dav raws li kev ua kom khaus qis polymeric. Cov kev sib piv hauv qab no qhia tau hais tias qhov sib txawv ntawm cov yam ntxwv molecular, kev ruaj ntseg profile, thiab kev tsim qauv siv los txhawb kev kuaj R & D.
|
Yam khoom |
Polyquaternium-1 (PQ-1) |
Benzalkonium Chloride (BAK) |
|
Hom Molecular |
High-molecular polymeric quaternary ammonium |
Me-molecule quaternary ammonium ntsev |
|
Ocular Cytotoxicity (In-vitro) |
Tsawg cytotoxicity; Tsis tshua muaj nkag mus rau corneal cell membranes |
Kev pheej hmoo ntawm cytotoxic ntau dua; yooj yim cell nkag mus ntawm cov pa tshuaj |
|
Irritation Profile |
Cov kab mob me me, haum rau rhiab ocular mis R & D |
Tej zaum ocular irritation nrog rau lub sij hawm ntev rov raug |
|
Antimicrobial Mechanism |
Deg adsorption & membrane cuam tshuam (bacteriostatic) |
Sib sib zog nqus cell nkag tau & ceev bactericidal nyhuv |
|
Kev sib haum xeeb |
Incompatible nrog anionic surfactants thiab anionic polymers |
Compatible nrog feem ntau excipients |
|
Daim ntawv thov Focus |
Tiv tauj lens daws, ntau koob tshuaj qhov muag tee, tsis tshua muaj ophthalmic prototypes |
General eye drops, cosmetic thiab industrial antiseptic qauv |
|
Residual Stimulation Risk |
Tsawg residual stimulation tom qab ntxuav lub lens |
Ib qho yooj yim residue tsub zuj zuj ntawm lub lens nto |
|
Formula Upgrade tus nqi |
Zoo tagnrho rau tiam tom ntej kev nyab xeeb ophthalmic formulation iteration |
Nqi-zoo tab sis txwv nyob rau hauv high-standard rhiab qauv |
Ntim & Shipping
Ntim feature: Nitrogen-purged lub tshuab nqus tsev aluminium ntawv ci puab lub hnab nrog desiccant tiv thaiv ya raws (tseem ceeb rau cov khoom siv hygroscopic)
Qauv ntau thiab tsawg: 100 mg / 1 g / 5 g, ntim rau hauv thawv.
Qhov ntau thiab tsawg: Custom nitrogen-sealed bulk ntim; custom packing muaj nyob rau ntawm kev thov.
Shipping condition: Standard chav tsev kub tus me nyuam; txias-chain shipping xaiv tau raws li qhov kev thov.
Lub Sijhawm Lead: Cov khoom hauv Tshuag hauv 1-3 hnub ua haujlwm tom qab lees paub qhov kev txiav txim.
Kev thauj mus los: Kev nthuav qhia thoob ntiaj teb rau cov qauv; huab cua freight / hiav txwv freight rau bulk xaj.
Cov ntaub ntawv muab: COA, SDS-MSDS, Daim Ntawv Teev Npe, Daim Ntawv Pov Thawj Ua Lag Luam.
Daim ntawv ceeb toom: Tus neeg tau txais kev lav phib xaub rau cov se hauv zos ntshuam, lub luag haujlwm thiab cov cai tswj hwm.
Cov lus teb rau cov neeg siv khoom
Hu rau PAGE
Yog tias koj tab tom nrhiav rau ib tus neeg muag khoom txhim khu kev qha ntawm Polyquaternium-1 (PQ-1, Polidronium Chloride, CAS 75345-27-6), peb muab ntau qhov ntau thiab tsawg los ntawm cov qauv kuaj me me mus rau cov khoom siv raw khoom. Cov ntim tshwj xeeb nitrogen-flushed los tiv thaiv noo noo yog siv rau cov khoom siv hygroscopic heev. COA, SDS-MSDS thiab cov ntaub ntawv ntsig txog kev lis kev cai tuaj yeem muab tau. Ua siab zoo xa koj cov lus nug rau kuv cov ntaub ntawv, peb pab pawg muag khoom yuav teb sai.
1.Nrhiav txoj kev:
Email: alice@xaheshun.com
whatspp: +8618509260106
Online instant messaging
2. Hu rau cov ntaub ntawv:
Lub npe: Alice
Xov tooj: +8618509260106
Email: alice@xaheshun.com
FAQ
Q: Nws cov yam ntxwv solubility yog dab tsi?
A: me ntsis soluble hauv dej thiab DMSO; sparingly soluble nyob rau hauv rhuab methanol; xyaum insoluble hauv ethanol thiab acetone.
Q: Kuv yuav tsum ua raws li kev cia khoom dab tsi?
A: Khaws kom nruj thiab tsis txhob ya raws. Lub sijhawm luv cia ntawm 2-8 degree; Lub sij hawm ntev cia pom zoo ntawm -20 degree. Lub neej ua haujlwm tsis tau qhib yog 2 xyoos.
Q: Cov ntaub ntawv dab tsi uas koj tuaj yeem muab tau?
A: COA, SDS-MSDS muaj. HPLC daim ntawv xeem tuaj yeem muab tau raws li cov neeg siv khoom thov.
Q: Puas yog Polyquaternium-1 tau tshaj anionic excipients?
A: Tsis yog. Nws yog incompatible nrog anionic polymers thiab anionic surfactants, uas yuav ua rau nag lossis daus thiab poob ntawm preservative kev ua tau zoo. Kev ntsuam xyuas kev sib raug zoo tau qhia zoo rau txhua tus qauv.
Q: Kuv yuav tsum ua raws li kev cia khoom dab tsi?
A: Khaws kom nruj thiab tsis txhob ya raws. Lub sijhawm luv cia ntawm 2-8 degree; Lub sij hawm ntev cia pom zoo ntawm -20 degree. Lub neej ua haujlwm tsis tau qhib yog 2 xyoos.
Cim npe nrov: Tuam Tshoj siab purity polyquaternium-1 cas 75345-27-6 manufacturers, lwm tus neeg, Hoobkas
