| Khoom npe | Hypromellose Acetate Succinate |
| Lub Npe | Hypromellose Acetate Succinate (HPMCAS) |
| CAS Nr. | 71138‑97‑1 |
| Qhov tshwm sim | Dawb rau me ntsis daj hmoov / nplua granules, me ntsis acetic-acid tsw |
| Hydroxypropoxy purity | 4.0‑23.0 % |
| Pharmacopoeia Standard | USP-NF, JP, EP, ChP |
| Solubility | Insoluble nyob rau hauv cov dej ntshiab & gastric kua |
| Daim ntawv pov thawj | FDA, GMP, ISO, MSDS |
| Packga | 25 kg fiber nruas nrog PE liner; Cov qauv me me: 100 g-5 kg aluminium foil hnab |
| Cia | Khaws cia, qhuav, txias, tsis txhob ya raws, ncaj qha tshav ntuj thiab kub kub; hygroscopic khoom |
| Txee-Lub neej | 24 Lub Hlis |
Khoom Description
Hypromellose Acetate Succinate yog dab tsi?
Hypromellose Acetate Succinate (HPMCAS, CAS 71138-97-1) yog compendial-qib cellulose-based enteric polymer excipient raws li USP-NF. Muaj nyob rau hauv LG, MG, HG qib nrog pH-responsive solubility. Feem ntau yog siv rau cov txheej txheej enteric thiab cov khoom tawg yooj yim los txhawb bioavailability ntawm cov tshuaj tsis zoo soluble rau kev tsim tshuaj.
Zoo sib xws Pharmaceutical Excipients rau HPMCAS, saib hauv qab no:
| Khoom npe | CAS Nr. |
| Hypromellose Phthalate (HPMCP) | 9050‑31‑1 |
| Cellulose Acetate Phthalate (CAP / Cellacefate) | 9004‑38‑0 |
| Polyvinyl Acetate Phthalate (PVAP) | 34481‑48‑6 |
| Methacrylic Acid Copolymer Hom A (Eudragit L series) | 25086‑15‑1 |
| Methacrylic Acid Copolymer Hom B (Eudragit S series) | 25086‑15‑1 |
| Kollicoat MAE 100P (Methacrylic acid-ethyl acrylate copolymer) | 52947‑94‑1 |
| Soluplus (Polyvinylcaprolactam-polyvinyl acetate-polyethylene glycol graft copolymer) | 88504‑27‑2 |
Daim ntawv thov ntawm Hypromellose Acetate Succinate
1. Pharmaceutical Industry (Primary Main Application, Pharmaceutical-Grade only)
Raws li cov tshuaj pharmacopoeia-qib polymer excipient lub rooj sib tham USP-NF, EP thiab JP cov kev cai, Hypromellose Acetate Succinate yog siv rau cov txheej txheej enteric ntawm cov ntsiav tshuaj, pellets thiab granules, amorphous solid-dispersion cab kuj rau cov tshuaj tsis zoo-soluble (txhaj tshuaj kom qhuav, kub-melt capsules), thiab hloov kho cov kev tshawb fawb. generic & tshiab tshuaj.
Nws yog ib tug kws tshuaj excipient nkaus xwb, tsis yog ib tug active ingredient. Daim ntawv thov tiag tiag yuav tsum ua raws li cov cai hauv zos.
2.Nutraceutical & Functional Food Industry (Food-Qib HPMCAS Yuav Tsum Tau)
Tso cai raws li FDA GRAS rau cov khoom noj khoom haus nkaus xwb; txwv tsis pub rau cov zaub mov dav dav thiab mis mos. Siv rau enteric txheej ntawm probiotic ntsiav tshuaj / granules, micro-encapsulation ntawm cov vitamins & nroj tsuag rho tawm, thiab zaj duab xis-forming rau cov ntsiav tshuaj ntxiv. Kev txheeb xyuas cov zaub mov hauv zos yuav tsum tau ua ntej kev lag luam tawm.
Khoom noj khoom haus-qib qib yog yuav tsum tau rau saum toj no-hais nutraceutical daim ntaub ntawv. Cov khoom siv qib tshuaj tsis tuaj yeem siv ncaj qha rau kev tsim khoom noj.
3.Kab tshuaj pleev ib ce & Kev Kho Tus Kheej Kev Lag Luam (Cosmetic-Qib)
Ua kom zoo dua ntawm nws cov cuab yeej ua yeeb yaj kiab, Hypromellose Acetate Succinate tuaj yeem siv rau cov tshuaj pleev ib ce thiab tswj-tso matrix rau cov khoom xyaw nquag hauv cov ntshav. Txawm li cas los xij, nws tsis yog cov khoom siv tshuaj pleev ib ce tseem ceeb thiab muaj kev lag luam qis hauv kev kho tus kheej.
Yuav tsum tau ua kom zoo nkauj-qib specification. Cov neeg siv yuav tsum ua raws li cov qauv kev cai hauv cheeb tsam kom zoo nkauj ua ntej daim ntawv thov kev lag luam.
Cov txiaj ntsig ntawm Core Formulation
1.Adjustable pH-triggered plab hnyuv tso tawm
Peb qib kev lag luam LG, MG, HG nrog qhov sib txawv ntawm qhov sib txawv pH qhov tseem ceeb, ua kom yooj yim rau qhov chaw tsim tawm tsim rau cov ntsiav tshuaj, pellets thiab granules; tiv thaiv cov kua qaub-rhiab heev tiv thaiv cov kua hauv plab thiab txo qis kev pheej hmoo ntawm plab hnyuv.
2.Kev ua yeeb yaj kiab zoo heev
Cov ntaub ntawv tawv, uniform enteric txheej txheej; ua hauj lwm zoo rau ob qho tib si dej-raws li thiab organic solvent txheej txheej txheem, tsawg brittleness pheej hmoo piv rau cov tsoos enteric polymers.
3.Powerful stabilization rau amorphous khoom dispersion
Cov iav-hloov kub kub inhibits API recrystallization, txhawb nqa tshuaj supersaturation; boosts dissolution thiab bioavailability rau cov dej-soluble APIs tsis zoo. Tau tshaj kub-melt-extrusion (HME) thiab tshuaj tsuag-drying ntau lawm technologiesPMC
Ntim
| Hom kev txiav txim | Net nyhav | Ntim Ntim | Ntim Ntim |
| Qauv / Lab R & D | 100 g, 500 g | Vacuum-sealed multi-layer aluminium-foil barrier bag | Aluminium-foil hnab muab tso rau hauv lub thawv ntawv nrog kev poob siab-absorbing muab tub lim |
| Small-batch lag luam | 1 kg, 5 kg | Ob-txheej nqus tsev vacuum-sealed aluminium-foil hnab nrog desiccant | Pharmaceutical HDPE nruas / fiber nruas |
| Kev lag luam loj loj | 25 kg | Ob txheej txheej aluminium-foil liner + desiccant sab hauv | UN-qualified kws tshuaj fiber nruas |
Cov lus teb rau cov neeg siv khoom
Hu rau PAGE
Peb muab USP-NF / EP / JP raws HPMCAS suav nrog LG, MG, HG qib rau R&D thiab ntau lawm. Ob qho piv txwv thiab ntau qhov ntau yog muaj.
Thov hu rau peb saib cov qauv hauv qab no kom tau txais koj qhov kev tsocai.
1.Nrhiav txoj kev:
Email: alice@xaheshun.com
whatspp: +8618509260106
Online instant messaging
2. Hu rau cov ntaub ntawv:
Lub npe: Alice
Xov tooj: +8618509260106
Email: alice@xaheshun.com
FAQ
Q: Cov qauv tshuaj pharmacopoeia twg yog koj li HPMCAS ua raws?
A: Peb cov kws kho mob qib HPMCAS ua tau raws li USP-NF, EP thiab JP monograph cov cai. Cov ntaub ntawv txhawb nqa kev xeem muaj nyob rau thaum thov.
Q: Tus yam ntxwv solubility ntawm HPMCAS yog dab tsi?
A: Insoluble hauv gastric acidic kua thiab dej ntshiab. Dissolves nyob rau hauv plab hnyuv tsis siab tshaj qib-specific pH. Soluble nyob rau hauv acetone los yog ethanol-dichloromethane tov organic solvents.
Q: Cov ntaub ntawv txhawb nqa dab tsi koj tuaj yeem muab rau HPMCAS?
A: COA, MSDS, TSE-BSE nqe lus, hnyav-hlau & residual-solvent test reports. DMF-hais txog cov ntaub ntawv txhawb nqa tuaj yeem muab tau thaum thov.
Q: HPMCAS puas tuaj yeem siv rau cov khoom noj khoom haus ntxiv?
A: Tsuas yog cov zaub mov qib HPMCAS tuaj yeem siv rau cov khoom noj khoom haus raws li FDA GRAS tso cai. Nws yog txwv tsis pub noj cov zaub mov thiab cov mis mos. Kev tswj xyuas kev tswj hwm hauv zos yuav tsum tau ua ntej kev lag luam siv.
Q: Dab tsi yog qhov chaw cia khoom raug rau HPMCAS?
A: HPMCAS yog hygroscopic. Khaws ntim rau hauv qhov chaw txias, qhuav, tsis txhob ya raws thiab tshav ntuj ncaj qha. Reseal thawv sai sai tom qab qhib kom tiv thaiv caking.
Cim npe nrov: Tuam Tshoj hypromellose acetate succinate cas 71138-97-1 manufacturers, lwm tus neeg, Hoobkas
