|
Khoom npe |
Aviptadil Acetate |
|
Qhov tshwm sim |
Dawb rau tawm -dawb hmoov |
|
Assay |
99% los ntawm HPLC |
|
Molecular Formula |
C147H238N44O42S |
|
CAS Nr |
40077-57-4 |
|
Solubility |
H2O/DMSO |
|
Cia |
Txias qhov chaw qhuav (Cuav ntawm -20 degree, deb ntawm lub teeb) |
Khoom Description
Dab tsi yog Aviptadil Acetatepeptide?
Tshuaj hais lus, nws yog ib tug polypeptide muaj li ntawm 28 amino acids nrog ib tug molecular luj ntawm kwv yees li 3385.9. Raws li ib tug analogue ntawm VIP, nws simulates tag nrho cov physiological zog ntawm VIP, tshwj xeeb tshaj yog nws muaj zog vasodilation nyhuv.
Lossis koj tuaj yeem nkag siab tias nws yog ib qho tseem ceeb "kev taw qhia molecule" uas tuaj yeem khi rau receptors ntawm cov hlwb tshwj xeeb ntawm lub cev (tshwj xeeb tshaj yog hom II alveolar hlwb hauv lub ntsws) los ua lub luag haujlwm tiv thaiv thiab tswj xyuas.
Xi 'an Tongze tuaj yeem muab lwm yam khoom siv peptide, cov ntawv teev npe raws li hauv qab no, txais tos sab laj!
|
Khoom npe |
CAS Nr. |
|
Goralatide |
127103-11-1/120081-14-3 |
|
ARA-290 (Cibinetide) |
1208243-50-8 |
|
N-acetyl Semax Amidate |
2920938-90-3 |
|
N-AC-selank-amide |
N/A |
|
Aviptadil Acetate |
40077-57-4 |
|
GLP-1(1-37) |
87805-34-3 |
|
GIP (human) |
100040-31-1 |
|
N-Acetyl-Semax |
N/A |
|
N-Acetyl Selank |
N/A |
|
S-Phenylacetyl Larazotide |
N/A |
|
Dermorphin |
77614-16-5 |
|
PEG-MGF |
N/A |
|
Tau ntsib -enkephalin |
58569-55-4 |
|
Pramlintide Acetate |
196078-30-5 |
|
Dalargin |
81733-79-1 |
|
Abaloparatide |
247062-33-5 |
|
N-Acetyl Larazotide |
N/A |
|
Tib neeg |
330936-69-1 |
|
Adamax |
N/A |
COA ntawmAviptadil Acetatepeptide
|
Khoom npe |
Aviptadil Acetate |
CAS Nr |
40077-57-4 |
|
Hnub tsim khoom |
2025/09/03 |
Hnub Kawg |
2027/09/02 |
|
Batch Number |
TZB 20250703 |
Batch Quantity |
2020G |
|
Yam khoom |
Specification |
Cov txiaj ntsig |
|
Cov ntaub ntawv Organoleptic |
||
|
Qhov tshwm sim |
Dawb rau tawm -dawb hmoov |
Dawb hmoov |
|
tsw & saj |
Yam ntxwv |
Ua raws |
|
Kev txheeb xyuas
|
"HNMR Conforms to structure |
Ua raws |
|
LCMS Conform to MW |
Ua raws |
|
|
Cov yam ntxwv ntawm lub cev |
||
|
Purity (los ntawm HPLC) |
Ntau dua lossis sib npaug li 99.0% |
99.98% |
|
Poob rau ziab |
Tsawg dua lossis sib npaug li 0.5% |
0.18% |
|
Residue ntawm ignition |
Tsawg dua lossis sib npaug li 0.2% |
0.13% |
|
Hnyav Hlau |
Tsawg dua lossis sib npaug li 10ppm |
<10ppm |
|
Coj(Pb) |
Tsawg dua lossis sib npaug li 0.5ppm |
<0.05ppm |
|
Arsenic (As) |
Tsawg dua lossis sib npaug li 1.5ppm |
<0.005ppm |
|
Cadmium (Cd) |
Tsawg dua lossis sib npaug li 0.5ppm |
<0.005ppm |
|
Mercury (Hg) |
Tsawg dua lossis sib npaug li 3.0ppm |
Tsis pom |
|
Xaus |
Cov khoom ua raws li kev lag luam tus qauv thiab tsim nyog |
|
|
Cia |
Khaws rau hauv qhov chaw kaw zoo thiab qhuav nrog chav sov thiab tsis muaj lub hnub ci ncaj qha. |
|
|
Txee lub neej |
2 Xyoo Thaum Khaws kom zoo |
|
Daim ntawv thov ntawmAviptadil Acetatepeptide
Aviptadil acetate yog ib qho hluavtaws peptide analog ntawmVasoactive plab hnyuv Polypeptide (VIP)-7. Nws ua haujlwm los ntawm kev ua kom VPAC1 thiab VPAC2 receptors, uas muaj nyob rau hauv siab concentrations ntawm alveolar hom II (ATII) hlwb nyob rau hauv lub ntsws -2-8. Qhov kev ua kom no ua rau vasodilation, los tiv thaiv kev mob, thiab kev tiv thaiv ntawm alveolar hlwb tiv thaiv kev raug mob -2-8.
Cov lus hauv qab no qhia txog cov ntawv thov tseem ceeb thiab lawv txoj kev txhim kho tam sim no.
| Daim ntawv thov cheeb tsam | Cov xwm txheej tshwj xeeb | Cov xwm txheej tseem ceeb / Cov ntsiab lus |
|---|---|---|
| Ua pa nyuaj | Acute Respiratory Distress Syndrome (ARDS) | • FDA Orphan Drug Designation (2005) -1-6 • Tshawb nrhiav kab mob thiab tsis yog- kis kab mob -3 |
| COVID-19 Kev ua pa tsis ua haujlwm | • FDA Fast Track Designation -2-8 • Tshawb xyuas raws li ZYESAMI ™ (IV thiab nqus tau) los tiv thaiv kev loj hlob mus rau qhov ua tsis taus pa tseem ceeb -1-10 • Kev sim Phase II pom tau tias rov zoo sai dua thiab txo lub ntsws puas -5 |
|
| Cov mob vascular | Pulmonary Arterial Hypertension (PAH) | • FDA Orphan Drug Designation (2005) -4-6 • Tau raug soj ntsuam raws li ib qho kev kho inhalable -9 |
| Lwm yam kev tshawb nrhiav siv | Pulmonary Fibrosis | • Muaj peev xwm inhibit fibrosis kev loj hlob -7 |
| Sarcoidosis | • EMEA Orphan Drug Designation -2-8 • Tau dhau qhov kev sim theem 2 -2 |
|
| Pom zoo (Tsis yog- Ua pa) | Erectile Dysfunction | • Pom zoo hauv Scandinavia thiab ntau lub tebchaws nyob sab Europe (co-formulated nrog phentolamamine) |
Kev nyab xeeb thiab kev mob tshwm simntawm Aviptadil Acetatepeptide
Aviptadil feem ntau tau qhia txog kev nyab xeeb zoo hauv kev sim tshuaj.
- Cov teebmeem tshwm sim:Tsuas yog qhov xwm txheej tseem ceeb tshaj plaws uas tau tshaj tawm yogmob plab me mus rau nruab nrab(30% hauv cov neeg koom nrog kho vs. 1.5% hauv pawg placebo, p<.001) -2-8.
- Lwm yam teebmeem:Cov kab mob hypotension (tsis tshua muaj ntshav siab) tau pom tab sis ntawm cov nqi zoo ib yam li cov placebo pawg (25% vs . 18.5%, P=NS) -2-8.
- Tolerability:Cov kev tshawb fawb txog kev noj qab haus huv pab dawb qhia tau tias IV infusion yog qhov zoo - zam nrog qee qhov cuam tshuam rau ntshav siab, lub plawv dhia, lossis ECG
Daim ntawv ceeb toom tseem ceeb
Pom zoo Status:Thaum Aviptadil tau pom zoo rau erectile kawg hauv qee lub tebchaws nyob sab Europe, nws siv rau ARDS, COVID-19, thiab PAH tseem nyob.kev tshawb nrhiav lossis tsis tau txais kev pom zoo FDA zaum kawgrau cov indications -1-4. Phase II / III sim rau nqus tau Aviptadil hauv qhov mob hnyav COVID-19 tau teev tseg tias "tawm" -2-10.
Kev Tshawb Fawb Tsuas Siv:Aviptadil Acetate hmoov muaj los ntawm cov chaw muag tshuaj yog nruj me ntsis raukev tshawb fawb preclinical thiab kuaj tsuas yog siv xwbthiab tsis yog siv rau tib neeg kev kho mob
Ntim & Kev xa khoom
Cov lus teb rau cov neeg siv khoom
Hu rau PAGE
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Email: alice@xaheshun.com
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Online instant messaging
2. Hu rau cov ntaub ntawv:
Lub npe: Alice
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Email: alice@xaheshun.com
FAQ
Q: Peb puas tuaj yeem muab cov khoom lag luam cuam tshuam ntawm Aviptadil Acetatepeptide?
A: Yog, Peb tuaj yeem muab lwm yam peptides, txais tos los tham.
Q: Koj ua li cas kho qhov kev tsis txaus siab?
A: Ua ntej tshaj plaws, peb qhov kev tswj xyuas zoo yuav txo qhov teeb meem zoo rau zero. Yog tias muaj teeb meem zoo los ntawm peb, peb yuav xa cov khoom dawb rau koj los hloov lossis rov qab koj cov nyiaj poob.
Q: Kev ntim khoom tuaj yeem nqa tawm ntawm Aviptadil Acetatepeptide?
A: Tau kawg, nws tuaj yeem rov ntim dua. Piv txwv li, nws yog feem ntau siv hauv vials lossis khov -cov hmoov qhuav qhuav rau lub hom phiaj kev zoo nkauj. Peb tuaj yeem muab lawv txhua tus.
Q: Puas muaj luv nqi?
A: Tau kawg, txais tos hu rau peb. Nqe yuav txawv raws li qhov sib txawv. Rau ntau qhov ntau, peb yuav muaj luv nqi rau koj.Tam sim no, peb muaj cov ncauj lus kom ntxaws txog cov khoom luv nqi thiab cov khoom lag luam nrog cov khoom muag loj txhua lub hlis twg.
Q: Txawm tias kev pabcuam customized tuaj yeem muab tau
A: Peb muab kev pabcuam ODM / OEM thiab tuaj yeem tsim ua raws li cov qauv tsim. Peb muaj peb tus kheej tsim qauv uas tuaj yeem tsim thiab kho cov khoom ntiag tug, ntim khoom. Peb cov kev pabcuam customized los ntawm kev tsim cov khoom siv raw, tsim cov khoom lag luam / ntim khoom, mus rau kev tsim cov ntim khoom raws li kev cai, thiab tom qab ntawd mus rau ntim, xa cov pob ntawv, ib qho - nres cov kab ntau lawm, txais tos tuaj xyuas.
Cim npe nrov: Tuam Tshoj aviptadil acetate peptide manufacturers, lwm tus neeg, Hoobkas
